Malaria, Moderate to Severe Anaemia, and Malarial Anaemia in Children at Presentation to Hospital in the Mount Cameroon Area: A Cross-Sectional Study. (8th November 2016)

• Record Type: Journal Article
• Authors: Sumbele, Irene Ule Ngole; Sama, Sharon Odmia; Kimbi, Helen Kuokuo; Taiwe, Germain Sotoing
• Other Names: Canatan Duran Academic Editor.
• Is Part Of: Anemia. Volume 2016(2016)
• Publication Date: 2016-11-08
• Subjects: Anemia -- Periodicals; 616.152005
• DOI: 10.1155/2016/5725634
• Languages: English
• ISSNs: 2090-1267

Abstract

Abstract : Background . Malaria remains a major killer of children in Sub-Saharan Africa, while anaemia is a public health problem with significant morbidity and mortality. Examining the factors associated with moderate to severe anaemia (M d SA) and malarial anaemia as well as the haematological characteristics is essential. Methodology . Children (1–14 years) at presentation at the Regional Hospital Annex-Buea were examined clinically and blood samples were collected for malaria parasite detection and full blood count evaluation. Results . Plasmodium falciparum, anaemia, and malarial anaemia occurred in 33.8%, 62.0%, and 23.6% of the 216 children, respectively. Anaemia prevalence was significantly higher in malaria parasite positive children and those with fever than their respective counterparts. M d SA and moderate to severe malarial anaemia (M d SMA) were detected in 38.0% and 15.3% of the participants, respectively. The prevalence of M d SA was significantly higher in children whose household head had no formal education, resided in the lowland, or was febrile, while M d SMA was significantly higher in febrile children only. Children with M d SMA had significantly lower mean white blood cell, lymphocyte, and platelet counts while the mean granulocyte count was significantly higher. Conclusion . Being febrile was the only predictor of both M d SA and M d SMA. More haematological insult occurred in children with M d SMA compared to MdSA.