A Study on the Association between Low Maternal Serum Magnesium Level and Preterm Labour. (13th April 2014)

• Record Type: Journal Article
• Authors: Okunade, Kehinde S.; Oluwole, Ayodeji A.; Adegbesan-Omilabu, Maymunah A.
• Other Names: Taylor Anthony H. Academic Editor.
• Is Part Of: Advances in medicine. Volume 2014(2014)
• Publication Date: 2014-04-13
• Subjects: Medicine -- Periodicals; Clinical medicine -- Periodicals; Clinical Medicine; Clinical medicine; Medicine; Periodicals; Electronic journals; Periodicals; 610
• DOI: 10.1155/2014/704875
• Languages: English
• ISSNs: 2356-6752

Abstract

Abstract : Objectives. The study was aimed to assess the association between low maternal serum magnesium levels and preterm labour. Methods. It is a cross-sectional case-control study in which eligible participants were pregnant women admitted in labour within the labour ward complex of a Lagos tertiary hospital. Relevant data were extracted from the case records of these women and blood samples were obtained from all participants and serum magnesium levels measured. Results. The study showed that 36% of the study patients had varying degrees of hypomagnesaemia. The relative risk indicates that preterm labour is 1.83 times higher among the patients with low serum magnesium (less than 1.6 mg/dL). The mean difference in serum magnesium levels in both groups was statistically significant (P < 0.05 ). Conclusion. We can infer that low serum magnesium (hypomagnesaemia) is associated with preterm onset of labour. We can, also from this finding, formulate a proposition that would help in preventing preterm labour and birth with the use of prophylactic oral magnesium supplementation among patients with higher risk for development of preterm labour.