Time to peak velocity in the main pulmonary artery as a marker of persistent pulmonary hypertension in neonates. Issue 2 (21st December 2018)

• Record Type: Journal Article
• Authors: Gately, Callum; Patel, Harshad
• Is Part Of: Australasian journal of ultrasound in medicine. Volume 22:Issue 2(2019)
• Page Start: 104
• Page End: 110
• Publication Date: 2018-12-21
• Subjects: echocardiogram -- neonatal -- persistent pulmonary hypertension of the newborn; Ultrasonics in medicine -- Periodicals; Ultrasonic imaging -- Periodicals; Ultrasonic imaging; Ultrasonics in medicine; Periodicals; 616.075430
• DOI: 10.1002/ajum.12120
• Languages: English
• ISSNs: 1836-6864

Abstract

Abstract: Purpose: To assess right ventricular systolic time intervals, specifically, time to peak velocity (TPV) in the pulmonary artery as a marker of persistent pulmonary hypertension of the newborn (PPHTN). Methods: This was a retrospective case–control study of 30 infants with pulmonary hypertension requiring intensive care management. Cardiac ultrasounds were re‐analysed, comparing TPV measurements to a group of 31 controls who had cardiac ultrasounds performed for incidental murmurs with structurally normal hearts. Results: Time to peak velocity was significantly shorter in the PPHTN group compared to controls, 47 vs. 95 ms, respectively. This was statistically significant with a P‐value of <0.001. Conclusion: Time to peak velocity in the pulmonary artery is a useful marker of PPHTN in the first week of life. This measurement is especially useful if neither tricuspid regurgitation or a patent ductus are present for interrogation on ultrasound.