Cobalt catalyzed stereodivergent semi-hydrogenation of alkynes using H2O as the hydrogen source. Issue 39 (29th April 2019)

• Record Type: Journal Article
• Authors: Li, Kangkui; Khan, Ruhima; Zhang, Xuexin; Gao, Yang; Zhou, Yongyun; Tan, Heng; Chen, Jingchao; Fan, Baomin
• Is Part Of: Chemical communications. Volume 55:Issue 39(2019)
• Page Start: 5663
• Page End: 5666
• Publication Date: 2019-04-29
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc01970g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Cobalt-catalyzed stereodivergent semi-hydrogenation of internal alkynes to alkenes is developed. Abstract : Cobalt-catalyzed stereodivergent semi-hydrogenation of internal alkynes to alkenes is developed. The reaction proceeded through transfer hydrogenation under mild conditions using a base metal CoI2 as the catalyst, and H2 O/MeOH as the hydrogen source with Zn as the reductant. The E / Z -selectivity of the product could be switched by changing the solvent and by inclusion/exclusion of a bidentate phosphine ligand (dppe). This method provides a simple and cost effective pathway for the synthesis of 1, 2-dideuterioalkenes.