NIR light-responsive short peptide/2D NbSe2 nanosheets composite hydrogel with controlled-release capacity. Issue 19 (16th April 2019)

• Record Type: Journal Article
• Authors: Wu, Can; Liu, Jing; Liu, Bin; He, Suyun; Dai, Guoru; Xu, Bo; Zhong, Wenying
• Is Part Of: Journal of materials chemistry. Volume 7:Issue 19(2019)
• Page Start: 3134
• Page End: 3142
• Publication Date: 2019-04-16
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c8tb03326a
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : The design of light-responsive peptide hydrogels with controllable drug release characteristics is still a challenge. Abstract : The design of light-responsive peptide hydrogels with controllable drug release characteristics is still a challenge. Here, we fabricated a NIR light-responsive short peptide hydrogel by using a thermo-responsive short peptide hydrogel and PEGylated NbSe2 nanosheets, namely, the NbSe2 –PEG@YD hydrogel. Under NIR light irradiation, the hydrogel began to collapse owing to the local heating, leading to the release of the cargos. The hydrogel exhibited recoverability and the release rate of the cargos could be accurately modulated by the NIR light irradiation according to the requirement. The excellent biocompatibility of this hydrogel ensured that it could be further developed as a drug carrier for clinical application.