Post-traumatic Intraocular Leiomyosarcoma in a Domestic Bovine Calf (Bos primigenius taurus). (April 2019)

• Record Type: Journal Article
• Authors: Kleinschmidt, S.; Mammen, S.; Puff, C.
• Is Part Of: Journal of comparative pathology. Volume 168(2019)
• Page Start: 41
• Page End: 45
• Publication Date: 2019-04
• Subjects: domestic bovine calf -- eye -- leiomyosarcoma -- post traumatic; Veterinary pathology -- Periodicals; Veterinary therapeutics -- Periodicals; Pathology, Comparative -- Periodicals; Therapeutics -- Periodicals; Pathology, Veterinary -- Periodicals; 636.089607
• DOI: 10.1016/j.jcpa.2019.03.006
• Languages: English
• ISSNs: 0021-9975

Abstract

Summary: The present report describes a case of a post-traumatic ocular leiomyosarcoma in a calf ( Bos primigenius taurus ) including clinical, histopathological and immunohistochemical features. Following a traumatic episode, the animal developed opacification of the lens and shrinkage of the eye. Subsequently, the ocular lesion increased in size over a period of 6 weeks and reached up to 16 cm in diameter with infiltration into the cranium. At necropsy examination, the kidneys, liver and spleen exhibited multiple firm white metastases up to 2 cm in diameter. The mass was composed of closely-packed streams and bundles of neoplastic cells, which immunohistochemically expressed vimentin and alpha smooth muscle actin. Based on the anamnestic data, morphological appearance, distribution and immunohistochemical results, a diagnosis of a post-traumatic intraocular leiomyosarcoma was made. The tumour may have originated from cells lining the pectinate ligament of the ciliary body.