Complex Sleep Apnea Syndrome. (16th February 2014)

• Record Type: Journal Article
• Authors: Khan, Muhammad Talha; Franco, Rose Amy
• Other Names: Billiard Michel M. Academic Editor.
• Is Part Of: Sleep disorders. Volume 2014(2014)
• Publication Date: 2014-02-16
• Subjects: Sleep disorders -- Periodicals; 616.8498005
• DOI: 10.1155/2014/798487
• Languages: English
• ISSNs: 2090-3545

Abstract

Abstract : Complex sleep apnea is the term used to describe a form of sleep disordered breathing in which repeated central apneas (>5/hour) persist or emerge when obstructive events are extinguished with positive airway pressure (PAP) and for which there is not a clear cause for the central apneas such as narcotics or systolic heart failure. The driving forces in the pathophysiology are felt to be ventilator instability associated oscillation in PaCO2 arterial partial pressure of Carbon Dioxide, continuous cositive airway pressure (CPAP) related increased CO2 carbon dioxide elimination, and activation of airway and pulmonary stretch receptors triggering these central apneas. The prevalence ranges from 0.56% to 18% with no clear predictive characteristics as compared to simple obstructive sleep apnea. Prognosis is similar to obstructive sleep apnea. The central apnea component in most patients on followup using CPAP therap, has resolved. For those with continued central apneas on simple CPAP therapy, other treatment options include bilevel PAP, adaptive servoventilation, permissive flow limitation and/or drugs.