Erythrocyte Omega-3 Fatty Acid Content in Elite Athletes in Response to Omega-3 Supplementation: A Dose-Response Pilot Study. (1st June 2017)

• Record Type: Journal Article
• Authors: Drobnic, Franchek; Rueda, Félix; Pons, Victoria; Banquells, Montserrat; Cordobilla, Begoña; Domingo, Joan Carles
• Other Names: Amin Kamal A. Academic Editor.
• Is Part Of: Journal of lipids. Volume 2017(2017)
• Publication Date: 2017-06-01
• Subjects: Lipids -- Periodicals; Lipids; Lipids; Electronic journals; Periodicals; Periodicals; 572.57
• DOI: 10.1155/2017/1472719
• Languages: English
• ISSNs: 2090-3030

Abstract

Abstract : Introduction . Supplementation of Omega-3 fatty acids (n-3FA) in athletes is related to the anti-inflammatory and/or antioxidant effect and consequently its action on all the processes of tissue restoration and adaptation to physical stress. Objective . Evaluate the Omega-3 Index (O3Ix) response, in red blood cells, to supplemental EPA + DHA intake in the form of high purity and stable composition gums (G), in elite summer athletes. Method . Twenty-four summer sport athletes of both sexes, pertaining to the Olympic Training Center in Spain, were randomized to two groups (2G = 760 or 3G = 1140 mg of n-3 FA in Omegafort OKids, Ferrer Intl.) for 4 months. Five athletes and four training staff volunteers were control group. Results . The O3Ix was lower than 8% in 93.1% of all the athletes. The supplementation worked in a dose-dependent manner: 144% for the 3G dose and 135% for the 2G, bothp < 0.001, with a 3% significant decrease of Omega-6 FAs. No changes were observed for the control group. Conclusions . Supplementation with n-3FA increases the content of EPA DHA in the red blood cells at 4 months in a dose-dependent manner. Athletes with lower basal O3Ix were more prone to increment their levels. The study is registered with Protocol Registration and Results System (ClinicalTrials.gov) numberNCT02610270 .