Haemostasis in Thyroid Surgery: Collagen-Fibrinogen-Thrombin Patch versus Cellulose Gauze—Our Experience. (25th February 2016)

• Record Type: Journal Article
• Authors: Tartaglia, Nicola; Di Lascia, Alessandra; Lizzi, Vincenzo; Cianci, Pasquale; Fersini, Alberto; Ambrosi, Antonio; Neri, Vincenzo
• Other Names: Kamer Erdinc Academic Editor.
• Is Part Of: Surgery research and practice. Volume 2016(2016)
• Publication Date: 2016-02-25
• Subjects: Surgery -- Periodicals; 617.005
• DOI: 10.1155/2016/3058754
• Languages: English
• ISSNs: 2356-7759

Abstract

Abstract : Purpose . Postoperative hemorrhage is fortunately uncommon but potentially life-threatening complication of thyroid surgery that increases the postoperative morbidity and the hospital stay. In this study we compare the efficacy of collagen patch coated with human fibrinogen and human thrombin (CFTP) (group C) and oxidized regenerated cellulose gauze (group B) versus traditional hemostatic procedures (group A) in thyroid surgery. Methods . From January 2011 to December 2013, 226 were eligible for our prospective, nonrandomized, comparative study. Patients requiring a video-assisted thyroidectomy without drain, "near total, " or hemithyroidectomy were excluded. Other exclusion criteria were a diagnosis of malignancy, substernal goiter, disorders of hemostasis or coagulation, and Graves or hyperfunctioning thyroid diseases. Outcomes included duration of operation, drainage volume, and postoperative complications. Results . Our results show a significant reduction in drainage volume in group C in comparison with the other two groups. In group C there was no bleeding but the limited numbers do not make this result significant. There were no differences in terms of other complications, except for the incidence of seroma in group B. Conclusion . The use of CFTP reduces the drainage volume, potentially the bleeding complications, and the hospital stay. These findings confirm the efficacy of CFTP, encouraging its use in thyroid surgery.