Bidens pilosa Formulation Improves Blood Homeostasis and β-Cell Function in Men: A Pilot Study. (18th March 2015)

• Record Type: Journal Article
• Authors: Lai, Bun-Yueh; Chen, Tzung-Yan; Huang, Shou-Hsien; Kuo, Tien-Fen; Chang, Ting-Hsiang; Chiang, Chih-Kang; Yang, Meng-Ting; Chang, Cicero Lee-Tian
• Other Names: Yang Wen-Chin Academic Editor.
• Is Part Of: Evidence-based complementary and alternative medicine. Volume 2015(2015)
• Publication Date: 2015-03-18
• Subjects: Alternative medicine -- Periodicals; 615.505
• DOI: 10.1155/2015/832314
• Languages: English
• ISSNs: 1741-427X

Abstract

Abstract : B. pilosa has long been purported to have antidiabetes activity, but despite the advancement in phytochemistry and animal models of diabetes, no human clinical trials have been conducted to date. Here, we evaluated the effect of a B. pilosa formulation on fasting blood glucose (FBG), fasting serum insulin, and glycosylated hemoglobin A1c( H b A 1 c ) in diabetic subjects. The B. pilosa formulation reduced the level of FBG andH b A 1 c in diabetics but increased fasting serum insulin in healthy subjects. Moreover, combination of B. pilosa formulation with antidiabetic drugs had better glycemic control in diabetics. The homeostatic model assessment (HOMA) data suggested that the antidiabetic activity of this formulation was via improvement of β -cell function. We also tested the safety of the B. pilosa formulation in healthy subjects and observed no obvious side effects. We conclude that B. pilosa has potential as an antidiabetes treatment.