Audiomotor Integration in Minimally Conscious State: Proof of Concept!. (3rd September 2015)
- Record Type:
- Journal Article
- Title:
- Audiomotor Integration in Minimally Conscious State: Proof of Concept!. (3rd September 2015)
- Main Title:
- Audiomotor Integration in Minimally Conscious State: Proof of Concept!
- Authors:
- Naro, Antonino
Leo, Antonino
Cannavò, Antonino
Buda, Antonio
Bruno, Rocco
Salviera, Carlo
Bramanti, Placido
Calabrò, Rocco Salvatore - Other Names:
- Garraghty Preston E. Academic Editor.
- Abstract:
- Abstract : Patients suffering from chronic disorders of consciousness (DOC) are characterized by profound unawareness and an impairment of large-scale cortical and subcortical connectivity. In this study, we applied an electrophysiological approach aimed at identifying the residual audiomotor connectivity patterns that are thought to be linked to awareness. We measured some markers of audiomotor integration (AMI) in 20 patients affected by DOC, before and after the application of a repetitive transcranial magnetic stimulation protocol (rTMS) delivered over the left primary motor area (M1), paired to a transauricular alternating current stimulation. Our protocol induced potentiating of the electrophysiological markers of AMI and M1 excitability, paired to a clinical improvement, in all of the patients with minimally conscious state (MCS) but in none of those suffering from unresponsive wakefulness syndrome (UWS). Our protocol could be a promising approach to potentiate the functional connectivity within large-scale audiomotor networks, thus allowing clinicians to differentiate patients affected by MCS from UWS, besides the clinical assessment.
- Is Part Of:
- Neural plasticity. Volume 2015(2015)
- Journal:
- Neural plasticity
- Issue:
- Volume 2015(2015)
- Issue Display:
- Volume 2015, Issue 2015 (2015)
- Year:
- 2015
- Volume:
- 2015
- Issue:
- 2015
- Issue Sort Value:
- 2015-2015-2015-0000
- Page Start:
- Page End:
- Publication Date:
- 2015-09-03
- Subjects:
- Neuroplasticity -- Periodicals
612.82 - Journal URLs:
- https://www.hindawi.com/journals/np/ ↗
- DOI:
- 10.1155/2015/391349 ↗
- Languages:
- English
- ISSNs:
- 2090-5904
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 10272.xml