CT and MRI Findings of Soft Tissue Adult Fibrosarcoma in Extremities. (6th March 2018)

• Record Type: Journal Article
• Authors: Wang, Hexiang; Nie, Pei; Dong, Cheng; Li, Jie; Huang, Yonghua; Hao, Dapeng; Xu, Wenjian
• Other Names: Terreno Enzo Academic Editor.
• Is Part Of: BioMed research international. Volume 2018(2018)
• Publication Date: 2018-03-06
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2018/6075705
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Objective . To characterize and evaluate CT and MRI features of extremity soft tissue adult fibrosarcoma. Methods . CT and MRI images from 10 adult patients with pathologically proven fibrosarcomas were retrospectively analyzed with regard to tumor location, size, number, shape, margins, attenuation, signal intensity, and enhancement patterns on MR images. Additionally, the relationships between lesions, deep fascia, and change in adjacent bones were also assessed. Results . Nineteen tumor lesions in 10 patients were selected for this study. Eighteen lesions were lobulated and one was oval in shape. Most cases were located under the deep fascia, including seven cases that had a nodular lump adjacent to the deep fascia and one case that had broken lesion through the deep fascia. On CT, the adult fibrosarcomas mostly showed iso-attenuated soft tissue masses (n = 6 ). On MRI, all the cases (n = 9 ) displayed low signal on T1-weighted imaging (T1WI) and heterogeneous low and high intensity signals on T2-weighted imaging (T2WI), with band-like areas of low signal on both T1WI and T2WI. On contrast-enhanced MRI images, three cases showed heterogeneous peripheral enhancement and one case demonstrated a spoke-wheel-like enhancement. Eight cases showed muscle edema signals in the peritumoral muscle and one case involved adjacent bone. Conclusion . CT and MR imaging have respective advantages in diagnosing adult fibrosarcoma. Combined application of CT and MR is recommended for patients with suspected adult fibrosarcoma.