Lithium Toxicity in the Setting of Nonsteroidal Anti-Inflammatory Medications. (2nd April 2013)

• Record Type: Journal Article
• Authors: Hassan, Syed; Khalid, Fatima; Alirhayim, Zaid; Amer, Syed
• Other Names: Almirall J. Academic Editor.; Passadakis P. S. Academic Editor.; Zuo L. Academic Editor.
• Is Part Of: Case reports in nephrology. Volume 2013(2013)
• Publication Date: 2013-04-02
• Subjects: Nephrology -- Periodicals; Kidneys -- Diseases -- Periodicals; Nephrology; Kidneys -- Diseases; Nephrology; Periodicals; Electronic journals; Periodicals; 616.61
• DOI: 10.1155/2013/839796
• Languages: English
• ISSNs: 2090-6641

Abstract

Abstract : Lithium toxicity is known to affect multiple organ systems, including the central nervous system. Lithium levels have been used in the diagnosis of toxicity and in assessing response to management. There is evidence that nonsteroidal anti-inflammatory medications (NSAIDs) can increase lithium levels and decrease renal lithium clearance. We present a case of lithium toxicity, which demonstrates this effect and also highlights the fact that lithium levels do not correlate with clinical improvement, especially the neurological deficit.