A Case of Opioid-Induced Hyperalgesia. (3rd July 2018)

• Record Type: Journal Article
• Authors: Wall, Jillian; Chauhan, Alpna
• Is Part Of: Journal of pain & palliative care pharmacotherapy. Volume 32:Number 2/3(2018)
• Page Start: 158
• Page End: 160
• Publication Date: 2018-07-03
• Subjects: Opioid-induced hyperalgesia -- opiate -- pain -- neurotoxicity; Pain -- Treatment -- Periodicals; Analgesia -- Periodicals; Palliative treatment -- Periodicals; Analgesics -- Therapeutic use -- Periodicals; Pain -- drug therapy -- Periodicals; Pain -- prevention & control -- Periodicals; Palliative Care -- Periodicals; Analgesics -- therapeutic use -- Periodicals; 616.994
• DOI: 10.1080/15360288.2018.1546256
• Languages: English
• ISSNs: 1536-0288

Abstract

Abstract: We report the case of a 76 year old lady with metastatic breast cancer, who presented to a hospice in severe distress from uncontrolled pain despite an increase in her opioid dose, alongside generalised hypersensitivity and delirium. The clinical presentation suggested opioid-induced hyperalgesia (OIH). After reduction of the opioid dose, our patient significantly improved to the extent she was discharged home a few weeks later. This report aims to increase awareness of OIH, a clinical phenomenon which remains poorly understood and probably under recognised.