Demographic and Clinical Predictors of Trait Impulsivity in Parkinson's Disease Patients. (19th April 2018)

• Record Type: Journal Article
• Authors: Riley, Maddeson; Bakeberg, Megan; Byrnes, Michelle; Jefferson, Alexa; Ghosh, Soumya; Stell, Rick; Mastaglia, Frank L.; Hince, Dana; Anderton, Ryan S.
• Other Names: Pisani Antonio Academic Editor.
• Is Part Of: Parkinson's disease. Volume 2018(2018)
• Publication Date: 2018-04-19
• Subjects: Parkinson's disease -- Periodicals; Parkinson's disease -- Treatment -- Periodicals; 616.833005
• DOI: 10.1155/2018/9472120
• Languages: English
• ISSNs: 2090-8083

Abstract

Abstract : Background . Impulsive behaviour has become increasingly recognised as a neuropsychiatric complication of Parkinson's disease (PD). Thought to be a product of compromised cognitive control, the spectrum of impulsive behaviours in PD ranges from cognitive disinhibition to impulse control disorders (ICDs). Objective . At present, there are no indicators for trait impulsivity in PD. The objective of the current study was to identify demographic and clinical predictors of susceptibility to trait impulsivity in a cohort of PD patients. Methods . The current study assessed impulsivity using the Barratt Impulsiveness Scale 11 (BIS-11) in a cohort of 87 PD patients. General linear models (GLMs) were used to identify clinical and demographic variables predictive of heightened BIS-11 second-order attentional and nonplanning subscale scores. Results . Male gender, no history of smoking, postsecondary education, and heightened disease severity were predictive of increased BIS-11 attentional scores (p < 0.05 ). Similarly, male gender, after secondary education, and disease severity were predictive of increased BIS-11 nonplanning scores (p < 0.05 ). Contrary to previous reports, dopaminergic medication use was not a significant determinant of either BIS-11 subscale scores. Conclusions . Several demographic and clinical variables including male gender, no history of past smoking, after secondary education, and elevated disease severity are associated with impulsivity in PD.