Comparison of C-Reactive Protein and Serum Amyloid A Protein in Septic Shock Patients. (5th February 2008)

• Record Type: Journal Article
• Authors: Cicarelli, Domingos Dias; Vieira, Joaquim Edson; Benseñor, Fábio Ely Martins
• Other Names: Zijlstra Freek Academic Editor.
• Is Part Of: Mediators of inflammation. Volume 2008(2008)
• Publication Date: 2008-02-05
• Subjects: Inflammation -- Mediators -- Periodicals; Biological response modifiers -- Periodicals; Inflammation (Pathologie) -- Médiateurs; Immunomodulateurs; Biological response modifiers; Inflammation -- Mediators; Immunology; Autacoids; Immunologic Factors; Cell Adhesion Molecules; Cell Communication; Cytokines; Inflammation; Periodicals; Electronic journals; 616.0473
• DOI: 10.1155/2008/631414
• Languages: English
• ISSNs: 0962-9351

Abstract

Abstract : Septic shock is a severe inflammatory state caused by an infectious agent. Our purpose was to investigate serum amyloid A (SAA) protein and C-reactive protein (CRP) as inflammatory markers of septic shock patients. Here we evaluate 29 patients in postoperative period, with septic shock, in a prospective study developed in a surgical intensive care unit. All eligible patients were monitored over a 7-day period by sequential organ failure assessment (SOFA) score, daily CRP, SAA, and lactate measurements. CRP and SAA strongly correlated up to the fifth day of observation but were not good predictors of mortality in septic shock.