An Intervention Target for Myocardial Fibrosis: Autophagy. (2nd April 2018)

• Record Type: Journal Article
• Authors: Lu, Chunmiao; Yang, Yusong; Zhu, Yaping; Lv, Shichao; Zhang, Junping
• Other Names: Gotzmann Michael Academic Editor.
• Is Part Of: BioMed research international. Volume 2018(2018)
• Publication Date: 2018-04-02
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2018/6215916
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Myocardial fibrosis (MF) is the result of metabolic imbalance of collagen synthesis and metabolism, which is widespread in various cardiovascular diseases. Autophagy is a lysosomal degradation pathway which is highly conserved. In recent years, research on autophagy has been increasing and the researchers have also become cumulatively aware of the specified association between autophagy and MF. This review highlights the role of autophagy in MF and the potential effects through the administration of medicine.