Occurrence of Pasteurella multocida among pigs with respiratory disease in China between 2011 and 2015. Issue 1 (December 2017)

• Record Type: Journal Article
• Authors: Liu, Huisheng; Zhao, Zhanqin; Xi, Xiaojian; Xue, Qiao; Long, Ta; Xue, Yun
• Is Part Of: Irish veterinary journal. Volume 70:Issue 1(2017)
• Page Start: 1
• Page End: 6
• Publication Date: 2017-12
• Subjects: Pasteurella multocida -- Bordetella bronchiseptica -- Swine -- Respiratory pathogen -- Co-infection; Veterinary medicine -- Periodicals; Veterinarians -- Ireland -- Periodicals; 636.08909417
• DOI: 10.1186/s13620-016-0080-7
• Languages: English
• ISSNs: 2046-0481

Abstract

Abstract Background Prior to the 1990s, P. multocida capsular serogroup A was the most prevalent in China, followed by serogroups B and D. Thirty years later, serogroup D became the most prevalent, followed by serogroups A and B. However, theP. multocida capsular serogroups currently circulating in China remain unclear. Therefore, the aim of the present study was to provide an update onP. multocida serogroups isolated from diagnostic samples collected from clinically diseased pigs in Central and Eastern China from 2011 to 2015. Results Between February 2011 and October 2015, 296 isolates ofPasteurella multocida were collected from 3212 pigs with clinical respiratory disease in 12 provinces of China (isolation rate of 9.2%). Of the 296 collected isolates, 146 (49.3%) wereP. multocida capsular type A, 141 (47.6%) were capsular type D, and one was capsular type B.Streptococcus suis (94/193; 48.7%), Haemophilus parasuis (76/193; 39.3%), Escherichia coli (53/193; 27.5%), andBordetella bronchiseptica (26/193; 13.5%) were frequently isolated together withP. multocida. A total of 14 toxigenicP. multocida strains co-isolated with other pathogens from 32 cases of atrophic rhinitis were classified into serogroup D. The virulence ofP. multocida capsular type A isolates was higher than that of capsular type D isolates based on LD50 studies in mice. Conclusions Over the past 5 years, P. multocida capsular type A was the most frequently isolated from diagnostic submissions in Central and Eastern China, followed by serogroups D and B.