Aspirin use and bleeding volume in skin cancer patients undergoing surgery: a randomized controlled trial. Issue 1 (December 2016)

• Record Type: Journal Article
• Authors: Engheta, Arman; Hadadi Abianeh, Shahryar; Atri, Ali; Sanatkarfar, Mehdi
• Is Part Of: Daru. Volume 24:Issue 1(2016)
• Page Start: 1
• Page End: 3
• Publication Date: 2016-12
• Subjects: Acetyl salicylic acid -- Skin cancer -- Surgery -- Bleeding -- Complication -- Aspirin; Pharmacology -- Periodicals; Drug development -- Periodicals; Pharmaceutical chemistry -- Periodicals; 615.19
• DOI: 10.1186/s40199-016-0159-4
• Languages: English
• ISSNs: 1560-8115

Abstract

Abstract ᅟ We investigated the occurrence of bleeding complications in patients who underwent skin tumor surgery and compared it between Aspirin users and a placebo control group. In this double blind randomized controlled trial, 32 patients who continued taking aspirin (intervention group) and 38 patients who stopped taking Aspirin (placebo group) before surgery were compared in terms of intraoprative and postoperative bleeding problems, hematoma and local signs of coagulopathy. There was no statistically significant difference in intraoprative bleeding between the study groups (P = 0.107). We concluded that continuation of Aspirin therapy had no significant effect on bleeding complications in patients who underwent skin tumor surgery. Trial registration IRCT201602049768N5 Graphical abstract Flow chart of the study process and its final finding