Common Bile-Duct Mucosa in Choledochoduodenostomy Patients — Histological and Histochemical Study. Issue 1 (1988)

• Record Type: Journal Article
• Authors: Eleftheriadis, E.; Tzioufa, V.; Kotzampassi, K.; Aletras, H.
• Is Part Of: HPB surgery. Volume 1:Issue 1(1988)
• Page Start: 15
• Page End: 20
• Publication Date: 1988
• Subjects: Biliary tract -- Surgery -- Periodicals; Liver -- Surgery -- Periodicals; Pancreas -- Surgery -- Periodicals; 617.55
• DOI: 10.1155/1988/85102
• Languages: English
• ISSNs: 0894-8569

Abstract

Abstract : We describe the histological and histochemical changes of the common bile-duct mucosa in specimens obtained by means of peroral cholangioscopy, 1–12 years after choledochoduodenal anastomosis. Our findings — hyperplasia of the superficial epithelium, metaplastic goblet cells containing predominantly acid sialomucins, and pyloric-like gland formation containing neutral mucins — express a morphological and functional differentiation of the common bile-duct mucosa that probably facilitates its survival in a different environment. We consider that these adaptive changes may explain the uneventful long-term postoperative period of choledochoduodenostomized patients.