Spontaneous regression of locally advanced nonsmall cell lung cancer: A case report. Issue 31 (August 2018)

• Record Type: Journal Article
• Authors: Ooi, Kiat Huat; Cheo, Timothy; Soon, Gwyneth Shook Ting; Leong, Cheng Nang
• Other Names: NA. section editor.
• Is Part Of: Medicine. Volume 97:Issue 31(2018)
• Publication Date: 2018-08
• Subjects: lung cancer -- NSCLC -- spontaneous regression -- spontaneous remission -- untreated; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000011291
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Spontaneous regression of non-small cell lung cancer is exceptionally rare. Patient concerns: Treatment-related toxicity. Diagnoses: We report a case of a patient diagnosed with locally advanced non-small cell lung cancer. Interventions: The patient declined potentially curative treatment, and did not receive any anti-cancer treatment. Outcomes: He has survived more than two years since his initial diagnosis, maintaining his good performance status. Serial imaging with computed tomography scans showed tumour regression and near-complete resolution of his disease. Lessons: Spontaneous regression of non-small cell lung cancer, by virtue of its scarcity, has not been well-studied and is poorly understood. Further studies are required, in order to clarify the mechanisms by which spontaneous regression occurs, and possibly identify new targets for cancer treatment. Abstract : Supplemental Digital Content is available in the text