Achieving Reliable Diagnosis in Late Breast Implant Seromas: From Reactive to Anaplastic Large Cell Lymphoma. (March 2019)

• Record Type: Journal Article
• Authors: Di Napoli, Arianna
• Is Part Of: Plastic and reconstructive surgery. Volume 143(2019)Supplement 3
• Publication Date: 2019-03
• Subjects: Surgery, Plastic -- Periodicals; 617.95205
• DOI: 10.1097/PRS.0000000000005565
• Languages: English
• ISSNs: 0032-1052

Abstract

Abstract : Summary: Late onset of fluid collection surrounding breast implants may represent a serious issue when considering the possibility of breast implant–associated anaplastic large cell lymphoma, a newly recognized type of T-cell malignancy. However, many other factors, including trauma and infections, may be implicated in the formation of non-neoplastic periprosthetic delayed effusions. An appropriate management of late seromas, consisting of ultrasound-guided fluid drainage, cultures, cytology, and immunocytochemical and T-cell clonality studies, should be performed to achieve a correct and prompt diagnosis of breast implant–associated anaplastic large cell lymphoma. Criticisms in the diagnosis of late peri-implant effusions are here discussed in detail.