MAPT mutation associated with frontotemporal dementia and parkinsonism (FTDP-17). (1st December 2016)

• Record Type: Journal Article
• Authors: Haussmann, Robert; Wysocki, Marek; Brandt, Moritz D.; Hermann, Andreas; Donix, Markus
• Is Part Of: International psychogeriatrics. Volume 29:Number 5(2017:May)
• Page Start: 869
• Page End: 871
• Publication Date: 2016-12-01
• Subjects: frontotemporal dementia, -- dementia, -- genetics, -- Parkinson's disease; Geriatric psychiatry -- Periodicals; 618.9768905
• DOI: 10.1017/S1041610216002192
• Languages: English
• ISSNs: 1041-6102

Abstract

ABSTRACT: We present a 56-year-old patient suffering from frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17). The history included a three-generation pedigree and the patient was found to be a mutation carrier. The diagnosis was hindered by late appearance of the hypokinetic movement disorder. For clinicians, it is important to consider rare neurodegenerative disease variants in early-onset familial dementia syndromes with behavioral, cognitive, and motor symptoms.