Favorable outcomes of prepackaged low‐residue diet on bowel preparation for colonoscopy: Endoscopist‐blinded randomized controlled trial. Issue 5 (24th October 2018)

• Record Type: Journal Article
• Authors: Lee, Jung Won; Choi, Joon Young; Yoon, Hyuk; Shin, Cheol Min; Park, Young Soo; Kim, Nayoung; Lee, Dong Ho
• Is Part Of: Journal of gastroenterology and hepatology. Volume 34:Issue 5(2019)
• Page Start: 864
• Page End: 869
• Publication Date: 2018-10-24
• Subjects: ascorbic acid -- bowel preparation solutions -- colonoscopy -- low‐residue diet -- polyethylene glycol; Gastroenterology -- Periodicals; Digestive organs -- Diseases -- Periodicals; Liver -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Liver Diseases -- Periodicals; 616.33
• DOI: 10.1111/jgh.14499
• Languages: English
• ISSNs: 0815-9319

Abstract

Abstract: Background and Aim: 2 L polyethylene glycol plus an ascorbic acid (PEGA) is known to be as effective. However, 2 L polyethylene glycol‐based regimens are often still difficult for patients to tolerate. Therefore, we conducted this study to evaluate the potential of 1 L PEGA with prepackaged low‐residue diet (PLD) as an alternative to 2 L PEGA before colonoscopy. Methods: The subjects were randomly assigned to either of the two groups. The 2 L PEGA group received 2 L PEGA split regimen. The 1 L PEGA with PLD group received PLD on the day preceding colonoscopy and 1 L PEGA. All endoscopic procedures were performed by one physician who did not know patients allocation. Bowel preparation status were graded using Boston Bowel Preparation Score (BBPS). A questionnaire regarding tolerability and safety was administered. This trial is registered at ClinicalTrials.gov (NCT03329339). Results: A total of 173 patients completed the study (86 in the 2 L PEGA group and 87 in the 1 L PEGA with PLD group). Bowel preparation was adequate in 88.4% (76/86) of patients in the 2 L PEGA group and 93.1% of patients in the 1 L PEGA with PLD group (81/87, P = 0.28). The patients in the 1 L PEGA with PLD group had higher whole Boston Bowel Preparation Scale score ( P = 0.02) and expressed more satisfaction and willingness to repeat the procedure ( P < 0.01). There was no significant difference with respect to compliance or safety. Conclusion: 1 L PEGA with PLD showed equivalent efficacy, greater satisfaction, and more willingness to repeat compared with 2 L PEGA for bowel preparation.