A methodology for numerically analysing the hepatic artery haemodynamics during B-TACE: a proof of concept. Issue 5 (4th April 2019)

• Record Type: Journal Article
• Authors: Aramburu, Jorge; Antón, Raúl; Rivas, Alejandro; Ramos, Juan Carlos; Larraona, Gorka S.; Sangro, Bruno; Bilbao, José Ignacio
• Is Part Of: Computer methods in biomechanics and biomedical engineering. Volume 22:Issue 5(2019)
• Page Start: 518
• Page End: 532
• Publication Date: 2019-04-04
• Subjects: Liver cancer -- B-TACE -- haemodynamics -- computational fluid dynamics -- 0D modelling -- 3D modelling; Biomechanics -- Data processing -- Periodicals; Biomedical engineering -- Periodicals; Biomechanics -- Periodicals; Biomedical Engineering -- methods -- Periodicals; Computing Methodologies -- Periodicals; 612.7
• DOI: 10.1080/10255842.2019.1567720
• Languages: English
• ISSNs: 1025-5842

Abstract

Abstract: Balloon-occluded transarterial chemoembolisation (B-TACE) is an intraarterial transcatheter treatment for liver cancer. In B-TACE, an artery-occluding microballoon catheter occludes an artery and promotes collateral circulation for drug delivery to tumours. This paper presents a methodology for analysing the haemodynamics during B-TACE, by combining zero-dimensional and three-dimensional modelling tools. As a proof of concept, we apply the methodology to a patient-specific hepatic artery geometry and analyse two catheter locations. Results show that the blood flow redistribution can be predicted in this proof-of-concept study, suggesting that this approach could potentially be used to optimise catheter location.