Effect of nano copper on visceral organs and the contents of trace elements in weanling pigs. (3rd April 2019)

• Record Type: Journal Article
• Authors: Chang, Zhenyu; Zhang, Hui; Mehmood, Khalid; Luo, Min; Zhao, Yali; Nabi, Fazul; Wu, Xiaoxing; Tian, Xinxin; Liu, Xueting; Zhou, Donghai
• Is Part Of: Toxin reviews. Volume 38:Number 2(2019)
• Page Start: 115
• Page End: 120
• Publication Date: 2019-04-03
• Subjects: Nano copper -- trace elements -- liver -- kidney -- histopathological; Toxicology -- Periodicals; Toxins -- Periodicals; 615.905
• DOI: 10.1080/15569543.2017.1421559
• Languages: English
• ISSNs: 1556-9543

Abstract

Abstract: We determine the effect of nano copper on visceral organs and contents of trace elements in organs and serum in weanling pigs. Our results showed that following supplementary concentration with 25, 50 and 200 mg/kg/day of nano copper, contents of copper shows trend of increasing in liver, kidney and intestinal; and ferrum shows gradually decreasing. The histopathological examination showed hemolysis, degeneration, nucleus pycnosis in liver, while renal tubular epithelial cell exfoliation and lymphocyte infiltration were found in kidney on supplementation of high concentration of nano-copper. Therefore, dietary supplementation of nano-copper 25 mg/kg b.wt could be a potential substitute for weaning piglets.