Effects of extremely low-frequency electromagnetic fields on B16F10 cancer cells. (3rd April 2019)

• Record Type: Journal Article
• Authors: Tang, Jing-Yau; Yeh, Te-Wei; Huang, Yu-Ting; Wang, Min-Haw; Jang, Ling-Sheng
• Is Part Of: Electromagnetic biology and medicine. Volume 38:Number 2(2019)
• Page Start: 149
• Page End: 157
• Publication Date: 2019-04-03
• Subjects: Extremely low-frequency -- electromagnetic field -- B16F10 cancer cells -- MTT assay -- Schumann resonance frequency; Electrophysiology -- Periodicals; Electromagnetic Fields -- Periodicals; Electrophysiology -- Periodicals; Radiation, Nonionizing -- Periodicals; 574
• DOI: 10.1080/15368378.2019.1591438
• Languages: English
• ISSNs: 1536-8378

Abstract

ABSTRACT: This paper presents a method to inhibit B16F10 cancer cells using extremely low-frequency electromagnetic fields (ELF-EMFs) and to evaluate cell viability using MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide) assay. The study examined the effect of a natural EMF resonance frequency (7.83 Hz) and a power line frequency (60 Hz) on B16F10 cancer cells for 24 and 48 h. The B16F10 cancer cells were also exposed to sweep frequencies in several sweep intervals to quantitatively analyze the viability of cancer cells. The results yielded a 17% inhibition rate under 7.83 Hz compared with that of the control group. Moreover, sweep frequencies in narrow intervals (7.83 ± 0.1 Hz for the step 0.05 Hz) caused an inhibition rate of 26.4%, and inhibitory effects decreased as frequency sweep intervals increased. These results indicate that a Schumann resonance frequency of 7.83 Hz can inhibit the growth of cancer cells and that using a specific frequency type can lead to more effective growth inhibition.