Sulfamerazine Schiff-base complex intercalated layered double hydroxide: synthesis, characterization, and antimicrobial activity. Issue 4 (April 2019)

• Record Type: Journal Article
• Authors: Barnabas, Mary Jenisha; Parambadath, Surendran; Nagappan, Saravanan; Ha, Chang-Sik
• Is Part Of: Heliyon. Volume 5:Issue 4(2019)
• Publication Date: 2019-04
• Subjects: Materials science -- Materials chemistry -- Inorganic chemistry -- Chemical engineering; Research -- Periodicals; Medical sciences -- Periodicals; Natural history -- Periodicals; Social sciences -- Periodicals; Earth sciences -- Periodicals; Physical sciences -- Periodicals; 507.2
• DOI: 10.1016/j.heliyon.2019.e01521
• Languages: English
• ISSNs: 2405-8440

Abstract

Abstract: Cobalt (Co(II)) and copper (Cu(II)) complexes of sulfamerazine-salicylaldehyde (SS) ligand intercalated Mg/Al-layered double hydroxide [Co-SS-LDH/Cu-SS-LDH] were prepared for the antimicrobial application. Sulfamerazine and salicylaldehyde were mixed together and dissolved in methanol for the synthesis of SS ligand and modified further by the complexation with Co(II) and Cu(II) metal ions [Co-SS/Cu-SS]. The delaminating/restacking method was used to intercalate the Mg/Al-NO3 -LDH with the metal complexed ligands (Co-SS/Cu-SS). The obtained materials were analyzed using different characterization techniques to prove their successful synthesis and preparation. The antibacterial activity of the synthesized Co-SS-LDH/Cu-SS-LDH were checked by the inhibition zone method. The prepared hybrid materials showed good antimicrobial activity against both gram negative ( Escherichia coli, E. coli ) and gram positive ( Staphylococcus aureus, S. aureus ) bacteria.