Rhodium(III)-catalyzed direct C-7 sulfonamidation and amination of indolines with arylsulfonamides and trifluoroacetamide. Issue 20 (16th May 2019)

• Record Type: Journal Article
• Authors: Dong, Yaqun; Sun, Song; Yu, Jin-tao; Cheng, Jiang
• Is Part Of: Tetrahedron letters. Volume 60:Issue 20(2019)
• Page Start: 1349
• Page End: 1352
• Publication Date: 2019-05-16
• Subjects: Rhodium-catalyzed -- Indolines -- N-arylsulfonamides -- C–H amidation; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2019.03.069
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: Rhodium-catalyzed direct C-7 sulfonamidation and amination of indolines. Simple arylsulfonamides and trifluoroacetamide used as amide source. Catalytic system is highly convenient on mmol scale. Abstract: A rhodium-catalyzed direct C–H sulfonamidation and amidation of C-7 position of indolines by simple and commercially available arylsulfonamides and trifluoroacetamide has been developed, affording a series of N -arylsulfonamides and N -aryltrifluoroacetamides in moderate to excellent yields, respectively. Notably, this catalytic system is highly convenient on mmol scale.