A new β-tetralonyl glucoside from the Santalum album derived endophytic fungus Colletotrichum sp. GDMU-1. Issue 3 (1st February 2019)

• Record Type: Journal Article
• Authors: Liu, Weiyang; Chen, Senhua; Li, Jing; Yang, Xuemei; Yan, Chong; Liu, Hongju
• Is Part Of: Natural product research. Volume 33:Issue 3(2019)
• Page Start: 354
• Page End: 359
• Publication Date: 2019-02-01
• Subjects: β-tetralonyl glucoside -- Santalum album -- Colletotrichum sp -- anti-inflammatory activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2018.1452003
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new β -tetralonyl glucoside, methylberchemiaside (1 ), along with five known compounds (2–6 ) were isolated from a fungus Colletotrichum sp . GDMU-1 derived from the leaves of Santalum album . Their structures were determined by detailed analysis of spectroscopic data. All compounds were tested for the inhibitory effects on the nitric oxide (NO) production in lipopolysaccharide (LPS)-treated RAW264.7 cells. Among them, compounds4 and5 showed moderate anti-inflammatory activity with IC50 value of 30.4 and 8.9 μM, respectively. Abstract :