Oxidative stress, genotoxicity and histopathology biomarker responses in Mugil cephalus and Dicentrarchus labrax gill exposed to persistent pollutants. A field study in the Bizerte Lagoon: Tunisia. (September 2015)

• Record Type: Journal Article
• Authors: Ameur, Walid Ben; El Megdiche, Yassine; de Lapuente, Joaquin; Barhoumi, Badreddine; Trabelsi, Souad; Ennaceur, Soukaina; Camps, Lydia; Serret, Joan; Ramos-López, David; Gonzalez-Linares, Javier; Touil, Soufiane; Driss, Mohamed Ridha; Borràs, Miquel
• Is Part Of: Chemosphere. Volume 135(2015)
• Page Start: 67
• Page End: 74
• Publication Date: 2015-09
• Subjects: Pollution -- Genotoxicity -- Oxidative stress -- Histopathology -- Fish gill -- Bizerte Lagoon; Pollution -- Periodicals; Pollution -- Physiological effect -- Periodicals; Environmental sciences -- Periodicals; Atmospheric chemistry -- Periodicals; 551.511
• DOI: 10.1016/j.chemosphere.2015.02.050
• Languages: English
• ISSNs: 0045-6535

Abstract

Highlights: Biomarkers were evaluated in gill of two fish species from Bizerte Lagoon. Enzyme activities were lower in fish from the polluted site. DNA damage was higher in both fish species from the contaminated site. Gill histopathological analysis revealed alterations in fish from Bizerte Lagoon. Abstract: The use of biomarkers has become an important tool for modern environmental assessment as they can help to predict pollutants involved in the monitoring program. Despite the importance of fish gill in several functions (gaseous exchange, osmotic and ionic regulation, acid-base balance and nitrogenous waste) its use in coastal water biomonitoring focusing on protection and damage is scarce. This field study investigates biochemical (catalase, superoxide dismutase, lipid peroxidation), molecular (DNA integrity) and morphological (histology) parameters in gill of mullet ( Mugil cephalus ) and sea bass ( Dicentrarchus labrax ) and originating from Bizerte lagoon (a coastal lagoon impacted by different anthropogenic activities) and from the Mediterranean Sea (a reference site). Remarkable alterations in the activities of oxidative stress enzymes and DNA integrity in the tissue of the two studied fish species were detected in Bizerte Lagoon. The study of histopathological alterations of gills in both two fish species from Bizerte Lagoon suggest thickening of primary lamellae, cellular hyperplasia, aneurism, curving, shortening and fusion of secondary lamellae. The adopted approach, considering simultaneously protection responses and damaging effects, revealed its usefulness on the pollution assessment.