Transcutaneous oxygen pressure (TcPO2) and ulcer outcome in diabetic patients: Is there any correlation?. Issue 2 (March 2019)

• Record Type: Journal Article
• Authors: Zubair, Mohammad; Ahmad, Jamal
• Is Part Of: Diabetes & metabolic syndrome. Volume 13:Issue 2(2019)
• Page Start: 953
• Page End: 958
• Publication Date: 2019-03
• Subjects: Amputation rate -- Correlation -- Diabetic patients -- TcPO2 -- Ulcer outcomes; Diabetes -- Periodicals; Metabolism -- Disorders -- Periodicals; Diabetes Mellitus -- Periodicals; Metabolic Diseases -- Periodicals; Diabète -- Périodiques; Métabolisme, Troubles du -- Périodiques; Endocrinologie -- Périodiques; Diabète -- Physiopathologie -- Périodiques; Diabetes; Metabolism -- Disorders; Electronic journals; Periodicals; 616.462
• DOI: 10.1016/j.dsx.2018.12.008
• Languages: English
• ISSNs: 1871-4021

Abstract

Abstract: Background: Due to poor blood circulation, the prevalence of foot ulcer is extensively reported among diabetic patients. Diabetic neuropathy is the critical factor of diabetes that can affect the nerves. Objective: To examine the outcomes and correlation between TcPO2 and ulcer outcomes among diabetic patients. Material and methods: A prospective cohort design has been employed to compare and correlate TcPO2 group with ulcer outcomes. A total of 192 patients were enrolled, who underwent diagnosis for ulcer outcome. Descriptive analysis and Pearson Correlation were used for data analysis via SPSS version 20. Results: The prevalence of minor amputation among diabetic patients in 25–40 mmHg 75 (85.22%) and >40 mmhG 73 (84.88%) group is reported for ulcer outcome. Mostly diabetic patients were healed with intact skin (male = 36, female = 73), and improved ulcer healing (male = 23, female = 43). Correlation between ulcer size (p = .016), ABI (p = .044), TBI (p = .000), Adiponectin (p = .009), HbA1c (p = .033), and S. creatinine (p = .025) was significant with TcpO2 group. Conclusions: The study concluded that there is a positive and significant correlation between TcPO2 group and ulcer outcome. There is a positive association between TcPO2 baseline and degree of ulcer healing with intact skin.