Metabolically healthy status and BMI in relation to depression: A systematic review of observational studies. Issue 2 (March 2019)

• Record Type: Journal Article
• Authors: Malmir, Hanieh; Mirzababaei, Atieh; Moradi, Sajjad; Rezaei, Shahabeddin; Mirzaei, Khadijeh; Dadfarma, Alireza
• Is Part Of: Diabetes & metabolic syndrome. Volume 13:Issue 2(2019)
• Page Start: 1099
• Page End: 1103
• Publication Date: 2019-03
• Subjects: Obesity -- Metabolic syndrome -- Health -- Depression -- Systematic review; Diabetes -- Periodicals; Metabolism -- Disorders -- Periodicals; Diabetes Mellitus -- Periodicals; Metabolic Diseases -- Periodicals; Diabète -- Périodiques; Métabolisme, Troubles du -- Périodiques; Endocrinologie -- Périodiques; Diabète -- Physiopathologie -- Périodiques; Diabetes; Metabolism -- Disorders; Electronic journals; Periodicals; 616.462
• DOI: 10.1016/j.dsx.2019.01.027
• Languages: English
• ISSNs: 1871-4021

Abstract

Abstract: Aim: Findings of association between metabolically healthy status and BMI and risk of depression are controversial. This study aimed to assess the relation between metabolically healthy status and BMI and depression. Methods: All published studies up to 25 June 2018 were searched by using the databases of PubMed, ISI Web of Science, SCOPUS and Google Scholar and following key words were used: metabolically AND (healthy OR unhealthy OR benign) AND (overweight OR obes* OR "over weight") AND phenotype AND (depression OR depress* OR "depressive disorder"). Results: After screening title and abstract and considering inclusion criteria, 5 studies were found to be included in our study. Metabolically unhealthy obesity was associated with 30%–83% increased risk of depression and metabolically unhealthy non-obesity was associated with 19%–60% increased risk of depression. Metabolically healthy obesity was not associated with the risk of depression in all studies. Conclusions: In conclusion, metabolically health status and BMI are associated with risk of depression. Metabolically unhealthy situation increased risk of depression greater than metabolically healthy status.