Current use of autologous adipose tissue-derived stromal vascular fraction cells for orthopedic applications. Issue 1 (December 2017)

• Record Type: Journal Article
• Authors: Pak, Jaewoo; Lee, Jung; Park, Kwang; Park, Moonhee; Kang, Lin-Woo; Lee, Sang
• Is Part Of: Journal of biomedical science. Volume 24:Issue 1(2017)
• Page Start: 1
• Page End: 12
• Publication Date: 2017-12
• Subjects: Mesenchymal stem cell -- Stromal vascular fraction -- Autologous adipose tissue-derived stem cells -- Effectiveness and safety -- Orthopedic applications; Medical sciences -- Periodicals; 610.28
• DOI: 10.1186/s12929-017-0318-z
• Languages: English
• ISSNs: 1021-7770

Abstract

Abstract Autologous adipose stromal vascular fractions (SVFs) containing adipose tissue-derived stem cells (ASCs) are currently being used in clinical settings for various orthopedic applications for human patients. Due to its potential capability of regenerating cartilage, bone, and tendons, autologous adipose SVFs are being tried in treating patients with osteoarthritis (OA), chondromalacia, meniscus tear, osteonecrosis of the femoral head, and tendon injuries. Here, we have reviewed available human clinical studies with regard to patient applications of autologous adipose SVF containing ASCs, specifically assessing effectiveness and safety in the field of orthopedic disorders. All studies reviewed in this article presents potential benefits of autologous adipose SVF in various orthopedic applications without any serious side effects.