Failure of syndromic management due to drug-resistant Mycoplasma genitalium infection in South Africa: a case report. (April 2019)

• Record Type: Journal Article
• Authors: Maduna, Liteboho D; Laumen, Jolein GE; Radebe, Oscar; Kock, Marleen M; Peters, Remco PH
• Is Part Of: International journal of STD & AIDS. Volume 30:Number 5(2019)
• Page Start: 519
• Page End: 521
• Publication Date: 2019-04
• Subjects: Non-gonococcal urethritis -- bacterial disease -- urethritis (bacterial) -- bacterial disease -- Africa -- location -- men -- other -- treatment; Sexually transmitted diseases -- Periodicals; AIDS (Disease) -- Periodicals; 616.951
• DOI: 10.1177/0956462418820745
• Languages: English
• ISSNs: 0956-4624

Abstract

We report a case of management failure of male urethritis syndrome due to macrolide-resistant Mycoplasma genitalium in South Africa. We detected mutations in 23S rRNA and one of the quinolone resistance-determining regions. This report confirms that drug-resistant M. genitalium infection can undermine the effectiveness of syndromic management in Africa.