Two cases of multidrug-resistant genitourinary Mycoplasma genitalium infection successfully eradicated with minocycline. (April 2019)

• Record Type: Journal Article
• Authors: Glaser, Allison M; Geisler, William M; Ratliff, Amy E; Xiao, Li; Waites, Ken B; Gaisa, Michael
• Is Part Of: International journal of STD & AIDS. Volume 30:Number 5(2019)
• Page Start: 512
• Page End: 514
• Publication Date: 2019-04
• Subjects: Mycoplasma genitalium -- urethritis -- antibiotic resistance -- minocycline; Sexually transmitted diseases -- Periodicals; AIDS (Disease) -- Periodicals; 616.951
• DOI: 10.1177/0956462418816757
• Languages: English
• ISSNs: 0956-4624

Abstract

Mycoplasma genitalium (MG) infection is a sexually transmitted infection that causes up to 25% of nongonococcal urethritis (NGU). MG strains carrying genetic markers of antimicrobial resistance that may affect treatment outcomes are increasingly recognized as a public health concern. We present two cases of persistent MG NGU with strains carrying both macrolide and quinolone resistance-associated mutations that were eradicated successfully by an extended course of minocycline.