An epidemiological study to assess Plasmodium falciparum parasite prevalence and malaria control measures in Burkina Faso and Senegal. (December 2017)

• Record Type: Journal Article
• Authors: Diallo, Aldiouma; Sié, Ali; Sirima, Sodiomon; Sylla, Khadime; Ndiaye, Mahmadou; Bountogo, Mamadou; Ouedraogo, Espérance; Tine, Roger; Ndiaye, Assane; Coulibaly, Boubacar; Ouedraogo, Alphonse; Faye, Babacar; Ba, El; Compaore, Guillaume; Tiono, Alfred; Sokhna, Cheikh; Yé, Maurice; Diarra, Amidou; Bahmanyar, Edith; Boer, Melanie; Pirçon, Jean-Yves; Usuf, Effua
• Is Part Of: Malaria journal. Volume 16:Number 1(2017)
• Page Start: 1
• Page End: 12
• Publication Date: 2017-12
• Subjects: Malaria -- Burkina Faso -- Senegal -- Epidemiological study -- Parasite prevalence -- Risk factors -- Preventive interventions; Malaria -- Periodicals; 616.9362
• DOI: 10.1186/s12936-017-1715-1
• Languages: English
• ISSNs: 1475-2875

Abstract

Abstract Background Malariometric information is needed to decide how to introduce malaria vaccines and evaluate their impact in sub-Saharan African countries. Methods This cross-sectional study (NCT01954264) was conducted between October and November, 2013, corresponding to the high malaria transmission season, in four sites with Health and Demographic Surveillance Systems (DSS) [two sites with moderate-to-high malaria endemicity in Burkina Faso (Nouna and Saponé) and two sites with low malaria endemicity in Senegal (Keur Socé and Niakhar)]. Children (N = 2421) were randomly selected from the DSS lists of the study sites and were stratified into two age groups (6 months–4 years and 5–9 years). A blood sample was collected from each child to evaluate parasite prevalence ofPlasmodium falciparum and otherPlasmodium species and gametocyte density by microscopy, and rapid diagnosis test in the event of fever within 24 h. Case report forms were used to evaluate malaria control measures and other factors. Results Plasmodium falciparum was identified in 707 (29.2%) children, with a higher prevalence in Burkina Faso than Senegal (57.5 vs 0.9% of children). In Burkina Faso, prevalence was 57.7% in Nouna and 41.9% in Saponé in the 6 months–4 years age group, and 75.4% in Nouna and 70.1% in Saponé in the 5–9 years age group. Infections with otherPlasmodium species were rare and only detected in Burkina Faso. While mosquito nets were used by 88.6–97.0 and 64.7–80.2% of children in Burkina Faso and Senegal, other malaria control measures evaluated at individual level were uncommon. In Burkina Faso, exploratory analyses suggested that use of malaria treatment or any other medication within 14 days, and use of insecticide spray within 7 days decreased the prevalence of malaria infection; older age, rural residence, natural floor, grass/palm roof, and unavailability of electricity in the house were factors associated with increased malaria occurrence. Conclusions Plasmodium falciparum infection prevalence in children younger than 10 years was 57.5% in Burkina Faso and 0.9% in Senegal, and variability was observed, among others, by age, study site and malaria control measures.