Pre-operative immunotherapy with tumor cryoablation (cryo) plus ipilimumab (ipi) induces potentially favorable systemic and intratumoral immune effects in early stage breast cancer (ESBC) patients. Issue 1 (December 2015) - Page, David; Diab, Adi; Yuan, Jianda; Dong, Zhiwan; Soloman, Stephen; Patil, Sujata; Hudis, Clifford; Wolchok, Jedd; Norton, Larry; McArthur, Heather