Brønsted Acid‐Catalyzed Carbocyclization of 2‐Alkynyl Biaryls. Issue 9 (22nd March 2019)

• Record Type: Journal Article
• Authors: Gicquiaud, Julien; Hacıhasanoğlu, Antoine; Hermange, Philippe; Sotiropoulos, Jean‐Marc; Toullec, Patrick Y.
• Is Part Of: Advanced synthesis & catalysis. Volume 361:Issue 9(2019)
• Page Start: 2025
• Page End: 2030
• Publication Date: 2019-03-22
• Subjects: Alkynes -- Brønsted acid catalysis -- Phenanthrenes -- Electrophilic activation -- Cycloisomerization; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201801526
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Ortho‐alkynyl biaryls react in the presence of catalytic amount of Brønsted acids to give phenanthrenes in high yields under mild conditions. The activity and selectivity of this transformation are governed by the substitution pattern of the diarylalkyne moiety. Selectivity shifts are observed between the carbophilic Lewis and Brønsted acid‐catalyzed cycloisomerization involving alkyne activation. Abstract :