Circular RNAs in human cancer. Issue 1 (December 2017)
- Record Type:
- Journal Article
- Title:
- Circular RNAs in human cancer. Issue 1 (December 2017)
- Main Title:
- Circular RNAs in human cancer
- Authors:
- Wang, Yumin
Mo, Yongzhen
Gong, Zhaojian
Yang, Xiang
Yang, Mo
Zhang, Shanshan
Xiong, Fang
Xiang, Bo
Zhou, Ming
Liao, Qianjin
Zhang, Wenling
Li, Xiayu
Li, Xiaoling
Li, Yong
Li, Guiyuan
Zeng, Zhaoyang
Xiong, Wei - Abstract:
- Abstract CircRNAs are a novel type of RNAs. With the newly developed technology of next-generation sequencing (NGS), especially RNA-seq technology, over 30, 000 circRNAs have already been found. Owing to their unique structure, they are more stable than linear RNAs. CircRNAs play important roles in the carcinogenesis of cancer. The expression of circRNAs is correlated with patients' clinical characteristics, and circRNAs play a vital role in many aspects of malignant phenotypes, including cell cycle, apoptosis, vascularization, and invasion; metastasis as a RNA sponge, binding to RBP; or translation. Therefore, it is meaningful to further study the mechanism of interactions between circRNAs and tumors. The role of circRNAs as molecular markers or potential targets will provide promising application perspectives, such as early tumor diagnosis, therapeutic evaluation, prognosis prediction, and even gene therapy for tumors.
- Is Part Of:
- Molecular cancer. Volume 16:Issue 1(2017)
- Journal:
- Molecular cancer
- Issue:
- Volume 16:Issue 1(2017)
- Issue Display:
- Volume 16, Issue 1 (2017)
- Year:
- 2017
- Volume:
- 16
- Issue:
- 1
- Issue Sort Value:
- 2017-0016-0001-0000
- Page Start:
- 1
- Page End:
- 8
- Publication Date:
- 2017-12
- Subjects:
- Circular RNAs -- Cancer -- Splicing -- Biomarker -- Regulation
Cancer -- Molecular aspects -- Periodicals
616.994 - Journal URLs:
- http://molecular-cancer.biomedcentral.com/ ↗
http://pubmedcentral.gov/tocrender.fcgi?journal=117 ↗
http://www.molecular-cancer.com/start.asp ↗
http://link.springer.com/ ↗ - DOI:
- 10.1186/s12943-017-0598-7 ↗
- Languages:
- English
- ISSNs:
- 1476-4598
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 10014.xml