Fetal aortic valvuloplasty to prevent progression to hypoplastic left heart syndrome in utero. Issue 8 (14th March 2019)

• Record Type: Journal Article
• Authors: Crystal, Matthew A.; Freud, Lindsay R.
• Other Names: Strainic Dr. James P. guestEditor.
• Is Part Of: Birth defects research. Volume 111:Issue 8(2019)
• Page Start: 389
• Page End: 394
• Publication Date: 2019-03-14
• Subjects: congenital heart disease -- fetal cardiac intervention -- fetal echocardiography -- hypoplastic left heart syndrome -- prenatal diagnosis; Teratology -- Periodicals; Abnormalities, Human -- Periodicals; Congenital Abnormalities; Embryo, Mammalian -- abnormalities; Teratology; Abnormalities, Human; Teratology; Periodicals; Periodicals; 616.043
• DOI: 10.1002/bdr2.1478
• Languages: English
• ISSNs: 2472-1727

Abstract

Abstract : Advances in fetal echocardiography have allowed for the prenatal diagnosis of congenital heart disease and an understanding of its natural history in utero. This insight has led to the development of fetal cardiac intervention (FCI) for select defects to prevent significant morbidity or mortality postnatally. Fetal aortic valvuloplasty (FAV) may be performed to prevent progression to hypoplastic left heart syndrome, a severe form of congenital heart disease, in utero. The current review focuses on this type of FCI and discusses the history of FAV, the rationale for intervention, candidate selection, procedural technique, and outcomes to date. Finally, the importance of building a multidisciplinary team to perform FCI is addressed.