Acid anhydride coated carbon nanodots: activated platforms for engineering clicked (bio)nanoconstructs. Issue 16 (9th April 2019)

• Record Type: Journal Article
• Authors: Ortega-Muñoz, Mariano; Vargas-Navarro, Paula; Hernandez-Mateo, Fernando; Salinas-Castillo, Alfonso; Capitan-Vallvey, Luis Fermin; Plesselova, Simona; Salto-Gonzalez, Rafael; Giron-Gonzalez, M. Dolores; Lopez-Jaramillo, Francisco Javier; Santoyo-Gonzalez, Francisco
• Is Part Of: Nanoscale. Volume 11:Issue 16(2019)
• Page Start: 7850
• Page End: 7856
• Publication Date: 2019-04-09
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c8nr09459d
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : Reactive acid anhydride coated carbon nanodots perpared by water-free thermolysis of citric acid are a gateway for engineering clicked (bio)nanoconstucts. Abstract : Activated carbon nanodots functionalized with acid anhydride groups (AA-CNDs ) are prepared by one-pot water-free green thermolysis of citric acid. As a proof of concept of their capabilities as appealing and versatile platforms for accessing engineering nanoconstructs, the as-preparedAA-CNDs have been reacted to yield clickable CNDs. Their click bioconjugation with relevant recognizable complementary clickable sugars has led to multivalent CND-based glyconanoparticles that are non-toxic and biorecognizable. The accessibility and intrinsic reactivity ofAA-CNDs expand the current toolbox of covalent surface grafting methodologies and provide a wide range of potential applications for engineering (bio)nanoconstructs.