Antimicrobial therapy for asymptomatic bacteriuria or candiduria in advanced cancer patients transitioning to comfort measures. (1st March 2019)

• Record Type: Journal Article
• Authors: Datta, Rupak; Wang, Tianyun; Zhu, Mojun; Dembry, Louise Marie; Han, Ling; Allore, Heather; Quagliarello, Vincent; Juthani-Mehta, Manisha
• Is Part Of: Infection control and hospital epidemiology. Volume 40:Number 4(2019)
• Page Start: 470
• Page End: 472
• Publication Date: 2019-03-01
• Subjects: Nosocomial infections -- Epidemiology -- Periodicals; Health facilities -- Sanitation -- Periodicals; Hospital buildings -- Sanitation -- Periodicals; Cross Infection -- Periodicals; Epidemiology -- Periodicals; Hospitals -- Periodicals; Infection Control -- Periodicals; 614.44
• DOI: 10.1017/ice.2019.22
• Languages: English
• ISSNs: 0899-823X

Abstract

Abstract: Among 300 advanced cancer patients with potential urinary tract infection (UTI), 19 had symptomatic UTI. Among remaining patients (n = 281), 21% had asymptomatic bacteriuria or candiduria, and 14% received inappropriate therapy for 279 antimicrobial days. Bacteriuria or candiduria predicted antimicrobial therapy. At 10, 000 to <100, 000 CFU/mL, the incidence rate ratio [IRR] was 16.9 (95% confidence interval [CI], 6.0–47.2), and at ≥100, 000 CFU/mL, the IRR was 27.9 (95% CI, 10.9–71.2).