Ischemic Stroke Incidence in Patients With Microvascular Ocular Motor Palsy Versus Patients With Lacunar Ischemic Stroke. Issue 2 (March 2019)

• Record Type: Journal Article
• Authors: Beato-Coelho, José; Varela, Ricardo; Almendra, Luciano; Carvalho, Mário; Duque, Cristina; Patrício, Miguel; Sargento-Freitas, João; Freire, António; Lemos, João
• Is Part Of: Neurologist. Volume 24:Issue 2(2019)
• Publication Date: 2019-03
• Subjects: microvascular ocular motor palsy -- lacunar stroke -- vascular disease -- ischemic stroke incidence; Nervous System Diseases -- Periodicals; Nervous system -- Diseases -- Periodicals; Neurologie; 616.8
• DOI: 10.1097/NRL.0000000000000213
• Languages: English
• ISSNs: 1074-7931

Abstract

Abstract : Objective: Presumed microvascular ischemia is the most frequent cause of ocular motor palsy (OMP). Ischemic stroke incidence after an episode of microvascular OMP (mOMP) is not established, contrasting with other common vascular conditions, such as lacunar ischemic stroke (LS). We sought to compare the incidence of subsequent ischemic stroke between mOMP and LS populations. Methods: A retrospective observational analysis was conducted on acute patients presenting with either mOMP or LS. A propensity score match was applied to ensure a balance between groups. We compared the incidence of subsequent ischemic stroke during an 80-month follow-up. Results: A total of 110 patients were included in the study (57, mOMPs; 53, LS). During follow-up, the annual occurrence rate of ischemic stroke was 2.1% per year in mOMP group and 0.6% per year in the LS group. After performing Cox regression, we found no statistical significance difference between groups in the incidence of subsequent ischemic stroke ( P =0.801). Conclusions: Patients with presumed mOCP seem to share similar incidence of subsequent ischemic stroke with patients with LS. Presumed mOCP may be an underrecognized independent risk factor for ischemic stroke.