Complete genome sequence of the actinomycete Actinoalloteichus hymeniacidonis type strain HPA 177T isolated from a marine sponge. Issue 1 (December 2016)

• Record Type: Journal Article
• Authors: Schaffert, Lena; Albersmeier, Andreas; Winkler, Anika; Kalinowski, Jörn; Zotchev, Sergey; Rückert, Christian
• Is Part Of: Standards in genomic sciences. Volume 11:Issue 1(2016)
• Page Start: 1
• Page End: 8
• Publication Date: 2016-12
• Subjects: Actinoalloteichus -- Strictly aerobic -- Non-motile -- Gram-positive -- Non-acid-fast -- Branching vegetative hyphae -- Spore forming -- Secondary metabolite biosynthesis gene clusters; Genomics -- Periodicals; Genomics -- Periodicals; Genomics; Periodicals; 572.8605
• DOI: 10.1186/s40793-016-0213-3
• Languages: English
• ISSNs: 1944-3277

Abstract

Abstract Actinoalloteichus hymeniacidonis HPA 177T is a Gram-positive, strictly aerobic, black pigment producing and spore-forming actinomycete, which forms branching vegetative hyphae and was isolated from the marine spongeHymeniacidon perlevis . Actinomycete bacteria are prolific producers of secondary metabolites, some of which have been developed into anti-microbial, anti-tumor and immunosuppressive drugs currently used in human therapy. Considering this and the growing interest in natural products as sources of new drugs, actinomycete bacteria from the hitherto poorly explored marine environments may represent promising sources for drug discovery. AsA. hymeniacidonis, isolated from the marine sponge, is a type strain of the recently described and rare genusActinoalloteichus, knowledge of the complete genome sequence enables genome analyses to identify genetic loci for novel bioactive compounds. This project, describing the 6.31 Mbp long chromosome, with its 5346 protein-coding and 73 RNA genes, will aid theGenomic Encyclopedia of Bacteria and Archaea project.