Salmonella enterica serovar Typhi osteomyelitis in a young adult with sickle cell and thalassemia traits: A possible association. (2019)

• Record Type: Journal Article
• Authors: Stephanie, Stephanie; Schmalzle, Sarah A.
• Is Part Of: IDCases. Volume 15(2018)
• Publication Date: 2019
• Subjects: Salmonella -- Typhoid fever -- Osteomyelitis -- Sickle cell -- Thalassemia -- Hemoglobinopathy; Communicable diseases -- Periodicals; Communicable Diseases -- Case Reports; Communicable Diseases -- Periodicals; Communicable diseases; Periodicals; 616.9
• DOI: 10.1016/j.idcr.2018.e00478
• Languages: English
• ISSNs: 2214-2509

Abstract

Abstract: Salmonella osteomyelitis is known to occur in immunocompromised and sickle cell disease patients. It rarely occurs in other hosts. We present a case of chronic femoral osteomyelitis due to S. enterica serovar Typhi seen in a Maryland resident. Potential risk factors included traveling to an endemic area as well as a newly diagnosed sickle cell trait and thalassemia trait. It is postulated that less severe hemoglobinopathies may also contribute to an elevated risk of Salmonella osteomyelitis.