Course of disease in multifocal choroiditis lacking sufficient immunosuppression: a case report. (December 2016)

• Record Type: Journal Article
• Authors: Schroeder, Katharina; Meyer-ter-Vehn, Tobias; Fassnacht-Riederle, Heidi; Guthoff, Rainer
• Is Part Of: Journal of medical case reports. Volume 10:Number 1(2016)
• Page Start: 1
• Page End: 4
• Publication Date: 2016-12
• Subjects: Multifocal choroiditis -- Chorioretinal lesions -- Secondary CNV -- Bevacizumab -- Systemic immunosuppression -- Case report; Medicine -- Research -- Periodicals; Medicine -- Case studies -- Periodicals; 610.5
• DOI: 10.1186/s13256-016-1069-2
• Languages: English
• ISSNs: 1752-1947

Abstract

Abstract Background Multifocal choroiditis with panuveitis is a rare disease. The educational merit of this case presentation results from the good documentation and the impressive ocular fundus pictures. Case presentation We illustrate the 3-year course of disease in a 22-year-old myopic white woman with multifocal choroiditis with panuveitis and secondary choroidal neovascularization. The activity of the disease was evaluated clinically by optical coherence tomography and fluorescein angiography. Choroidal neovascularization was treated by intravitreal bevacizumab (2.5 mg/0.1 ml). Our patient lacked systemic therapy for the first 11 months because of noncompliance. Conclusions The case is remarkable as the delayed onset of peripheral lesions and the additional existence of high myopia made diagnosis difficult. In addition, it demonstrates that full outbreak of disease with multiple central and peripheral fundus lesions and secondary choroidal neovascularization can develop without systemic treatment.