E. coli bacteremia in comparison to K. pneumoniae bacteremia: influence of pathogen species and ESBL production on 7-day mortality. Issue 1 (December 2016)

• Record Type: Journal Article
• Authors: Leistner, R.; Bloch, A.; Gastmeier, P.; Schwab, F.
• Is Part Of: Antimicrobial resistance & infection control. Volume 5:Issue 1(2016)
• Page Start: 1
• Page End: 4
• Publication Date: 2016-12
• Subjects: ESBL -- Bacteremia -- Sepsis -- K. pneumoniae -- E. coli -- Enterobacteriaceae -- Mortality; Infection -- Treatment -- Periodicals; Drug resistance -- Periodicals; Drug Resistance, Microbial -- Periodicals; 616.9041
• DOI: 10.1186/s13756-016-0138-z
• Languages: English
• ISSNs: 2047-2994

Abstract

Abstract In a previous study, we demonstrated prolonged length of hospital stay in cases of extended-spectrum beta-lactamase (ESBL)-positiveK. pneumoniae bacteremia compared to bacteremia cases due toE. coli (ESBL-positive and –negative) and ESBL-negativeK. pneumoniae . The overall mortality was significantly higher in bacteremia cases resulting from ESBL-positive pathogens but also inK. pneumoniae cases disregarding ESBL-production. In order to examine whether pathogen species rather than multidrug resistance might affect mortality risk, we reanalyzed our dataset that includes 1.851 cases of bacteremia.