FDG PET and MRI Findings in a Case of Bing-Neel Syndrome. (April 2018)

• Record Type: Journal Article
• Authors: Bund, Caroline; Lhermitte, Benoît; De Seze, Jérôme; Kremer, Stéphane; Namer, Izzie-Jacques
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 4(2018)
• Publication Date: 2018-04
• Subjects: FDG PET/CT -- Bing-Neel syndrome -- MRI -- Waldenström disease; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002019
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 64-year-old man was admitted for expressive aphasia with lack of words. He had been diagnosed with Waldenström 4 years before. At that time, he received 6 cycles of single-agent fludarabine, and remission was obtained. Because of acute expressive aphasia, he underwent brain MRI, which showed frontoparietal and insular subcortical gadolinium enhancement; Bing-Neel syndrome was suspected. Fronto-temporo-insular hypometabolism and left parietal hypometabolism were highlighted on FDG PET/CT. Structural and functional brain imaging revealed impairment of brain areas due to white matter changes and reinforced the diagnosis.