Facile construction & modeling of a highly active thiacalixphenyl[4]arene-protected nano-palladium catalyst for various C–C cross-coupling reactions. (22nd March 2019) - Modi, Krunal
Abstract : A newly designed and synthesized thiacalixphenyl[4]arene tetraacetohydrazide (TPTAH ) has been utilized for the construction of palladium nanoparticles (TPTAH -PdNPs), which are found to be catalytically active for the C–C cross-coupling reactions such as the Suzuki–Miyaura, Heck, and Stille reactions. Abstract : The design and creation of thiacalixphenyl[4]arene tetraacetohydrazide (TPTAH ) has been utilized for the construction of palladium nanoparticles (PdNps). The molecular modelling studies give an insight into the surface properties ofTPTAH capped PdNps. The plausible reduction mechanism of Pd(ii ) to Pd(0) is due to the presence of hydrazide group on the periphery. The charge transfer for this reduction was initiated by the carbonyl group and N-atom.TPTAH behaves as a reducing and stabilizing agent for the formation of catalytically activeTPTAH -PdNps that were characterized by UV-Vis spectroscopy, selected area electron diffraction (SAED), transmission electron microscopy (TEM), and powder X-ray diffraction. TheTPTAH -PdNps with size 4 ± 2 nm were found to be catalytically active for C–C cross-coupling reactions such as the Suzuki–Miyaura, Heck, and Stille reactions.TPTAH -PdNps are superior to the conventional Pd catalyst in terms of yield, catalyst loading, reaction time, and recyclability.